hrp0092p3-273 | Late Breaking Abstracts | ESPE2019

Insulin Sensitivity as Homa at Start and End of HGH Treatment of Children with Congenital (C) Ighd and Mphd

Laron Zvi , Shmalia Mona , Kauli Rivka , Lilos Pnina

Background: Patients with congenital IGHD or MPHD develop adiposity already "in utero". The effects of growth hormone (GH) treatment on adipose tissue are controversial, many claiming that GH reduces body fat (1.2). In addition there are reports that long-term GH treatment causes glucose intolerance, insulin resistance, followed in some instances by diabetes (3).Objective: To determine whether long-term hGH treat...